🫀 Anatomy · Cardiovascular System

Memory tricks for the heart and vessels

Chambers, valves, conduction pathways, circulation routes — the cardiovascular system requires precise anatomical knowledge. These mnemonics make the heart's structure and function stick so you can recall it under exam pressure.

🫀 Cardiovascular System

Memory Tricks

Proven Mnemonics & Acronyms — fast to learn, hard to forget.

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Blood Flow Through the Heart
Lub-Dub: Right side to lungs · Left side to body
RA → RV → Pulmonary → Lungs → LA → LV → Aorta → Body
The complete path of blood through the heart — never get it backwards again
Deoxygenated blood returns from the body via the superior and inferior vena cava into the Right Atrium → through the tricuspid valve → Right Ventricle → through the pulmonary valve → Pulmonary arteries → Lungs (oxygenated) → Pulmonary veins → Left Atrium → through the mitral (bicuspid) valve → Left Ventricle → through the aortic valve → Aorta → Body. Remember: Pulmonary arteries carry DEoxygenated blood — the only arteries that do.
Vena cava
Superior + inferior → Right Atrium. Deoxygenated blood returns from body.
Tricuspid valve
Right AV valve — between RA and RV. 3 cusps.
Pulmonary valve
RV → pulmonary trunk → lungs. Semilunar valve.
Pulmonary veins
Return oxygenated blood to Left Atrium — only veins carrying oxygenated blood.
Mitral valve
Left AV valve — between LA and LV. Bicuspid (2 cusps). Most commonly diseased.
Aortic valve
LV → aorta → systemic circulation. Semilunar valve.
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🃏 Blood Flow Through the Heart
Blood flow through the heart — the path from vena cava to aorta?
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🃏 Answer
Lub-Dub: Right side to lungs · Left side to body
Vena cavaSuperior + inferior → Right Atrium. Deoxygenated blood returns from body.
Tricuspid valveRight AV valve — between RA and RV. 3 cusps.
Pulmonary valveRV → pulmonary trunk → lungs. Semilunar valve.
Pulmonary veinsReturn oxygenated blood to Left Atrium — only veins carrying oxygenated blood.
Mitral valveLeft AV valve — between LA and LV. Bicuspid (2 cusps). Most commonly diseased.
Aortic valveLV → aorta → systemic circulation. Semilunar valve.
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Heart Valves
Try Pulling My Aorta — TPMA
Tricuspid · Pulmonary · Mitral · Aortic — in order of blood flow
Four heart valves in order of blood flow — right to left
All four heart valves prevent backflow of blood. TPMA follows blood flow from right to left. Tricuspid (right AV valve) has 3 leaflets. Pulmonary semilunar valve separates RV from pulmonary trunk. Mitral (left AV, bicuspid) has 2 leaflets — most commonly affected in rheumatic fever. Aortic semilunar valve separates LV from aorta — aortic stenosis is the most common valve disease in adults.
Tricuspid
RA → RV. 3 cusps. Chordae tendineae prevent inversion.
Pulmonary
RV → pulmonary trunk. Semilunar — 3 half-moon shaped cusps.
Mitral
LA → LV. Bicuspid — 2 cusps. Most common in rheumatic fever.
Aortic
LV → aorta. Semilunar. Aortic stenosis most common adult valve disease.
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🃏 Heart Valves
Heart valves — the 4 in order of blood flow?
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🃏 Answer
Try Pulling My Aorta — TPMA
TricuspidRA → RV. 3 cusps. Chordae tendineae prevent inversion.
PulmonaryRV → pulmonary trunk. Semilunar — 3 half-moon shaped cusps.
MitralLA → LV. Bicuspid — 2 cusps. Most common in rheumatic fever.
AorticLV → aorta. Semilunar. Aortic stenosis most common adult valve disease.
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Cardiac Conduction
SA → AV → Bundle of His → Bundle Branches → Purkinje
Sinoatrial node → AV node → His → Left/Right branches → Purkinje fibers
The cardiac conduction pathway — in exact order
The SA node is the pacemaker of the heart — fires at 60-100 bpm naturally. Signal spreads through atria → AV node (delays signal 0.1 sec to allow atria to contract first) → Bundle of His → Left and Right bundle branches → Purkinje fibers (rapid spread through ventricles). If SA node fails: AV node takes over at 40-60 bpm. If AV node fails: ventricles pace themselves at 20-40 bpm.
SA node
Right atrium, pacemaker, 60-100 bpm. P wave on ECG.
AV node
Delays signal 0.1 sec — allows atria to finish contracting. PR interval on ECG.
Bundle of His
Only electrical connection between atria and ventricles.
Bundle branches
Left and right — carry signal down interventricular septum.
Purkinje fibers
Rapid spread through ventricular myocardium. QRS complex on ECG.
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🃏 Cardiac Conduction
Cardiac conduction — the pathway, in order?
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🃏 Answer
SA → AV → Bundle of His → Bundle Branches → Purkinje
SA nodeRight atrium, pacemaker, 60-100 bpm. P wave on ECG.
AV nodeDelays signal 0.1 sec — allows atria to finish contracting. PR interval on ECG.
Bundle of HisOnly electrical connection between atria and ventricles.
Bundle branchesLeft and right — carry signal down interventricular septum.
Purkinje fibersRapid spread through ventricular myocardium. QRS complex on ECG.
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Vessel Types
Away = Artery · Vein = Venue (returns)
Arteries carry blood AWAY from heart · Veins RETURN blood to heart
The fundamental distinction between arteries and veins
Arteries always carry blood AWAY from the heart — regardless of oxygen content. Veins always return blood TO the heart — regardless of oxygen content. The pulmonary arteries carry deoxygenated blood and the pulmonary veins carry oxygenated blood — this trips up many students. Capillaries are the site of gas and nutrient exchange — one cell thick. Arteries have thicker walls with more smooth muscle. Veins have thinner walls and valves to prevent backflow.
Arteries
Away from heart. Thick walls, high pressure, elastic. No valves.
Arterioles
Regulate blood flow to capillaries — control BP via vasoconstriction.
Capillaries
Exchange — one cell thick, site of O2/CO2/nutrient exchange.
Venules
Drain capillaries into veins.
Veins
Return to heart. Thin walls, low pressure, have valves. 60% of blood volume.
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🃏 Vessel Types
Blood vessel types — what does each do?
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🃏 Answer
Away = Artery · Vein = Venue (returns)
ArteriesAway from heart. Thick walls, high pressure, elastic. No valves.
ArteriolesRegulate blood flow to capillaries — control BP via vasoconstriction.
CapillariesExchange — one cell thick, site of O2/CO2/nutrient exchange.
VenulesDrain capillaries into veins.
VeinsReturn to heart. Thin walls, low pressure, have valves. 60% of blood volume.
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Coronary Arteries
LAD = Widow Maker · RCA = Right · LCx = Left Circumflex
Left Anterior Descending · Right Coronary Artery · Left Circumflex
Three major coronary arteries — and why the LAD has its nickname
The heart supplies itself via coronary arteries that arise from the aortic root just above the aortic valve. Left coronary artery divides into the LAD (supplies anterior LV and interventricular septum) and Left Circumflex (LCx, supplies lateral and posterior LV). Right Coronary Artery (RCA) supplies the right heart and SA/AV nodes. LAD occlusion is called the "widow maker" because it causes massive anterior MI with high mortality.
LAD
Left Anterior Descending — "widow maker." Anterior LV and septum.
LCx
Left Circumflex — lateral and posterior LV wall.
RCA
Right Coronary — right heart, SA node, AV node (inferior MI).
Coronary sinus
Venous drainage of heart → returns to right atrium.
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🃏 Coronary Arteries
Coronary arteries — what does each supply?
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🃏 Answer
LAD = Widow Maker · RCA = Right · LCx = Left Circumflex
LADLeft Anterior Descending — "widow maker." Anterior LV and septum.
LCxLeft Circumflex — lateral and posterior LV wall.
RCARight Coronary — right heart, SA node, AV node (inferior MI).
Coronary sinusVenous drainage of heart → returns to right atrium.
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Heart Wall Layers
PEM — Pericardium · Epicardium · Myocardium · Endocardium
Outside to inside — 4 layers of the heart wall
Four layers of the heart wall — from the outer sac to the inner lining
Pericardium: double-walled fibrous sac surrounding the heart. Fibrous pericardium (outer) anchors heart. Serous pericardium has parietal and visceral layers with pericardial fluid between — reduces friction. Epicardium = visceral pericardium = outermost layer of heart wall. Myocardium: cardiac muscle — thickest layer, does the pumping work. Endocardium: smooth inner lining of chambers and valves. Cardiac tamponade = fluid compression in pericardial sac.
Pericardium
Outer sac — fibrous (outer) + serous (inner). Pericardial fluid reduces friction.
Epicardium
Visceral pericardium — outermost heart wall layer. Coronary vessels run here.
Myocardium
Cardiac muscle — thickest layer. LV myocardium is thickest (high pressure).
Endocardium
Innermost — smooth lining of chambers and valves. Prevents clot formation.
Tamponade
Fluid compresses heart — Beck's triad: hypotension, JVD, muffled heart sounds.
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🃏 Heart Wall Layers
PEM
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🃏 Answer
PEM — Pericardium · Epicardium · Myocardium · Endocardium
PericardiumOuter sac — fibrous (outer) + serous (inner). Pericardial fluid reduces friction.
EpicardiumVisceral pericardium — outermost heart wall layer. Coronary vessels run here.
MyocardiumCardiac muscle — thickest layer. LV myocardium is thickest (high pressure).
EndocardiumInnermost — smooth lining of chambers and valves. Prevents clot formation.
TamponadeFluid compresses heart — Beck's triad: hypotension, JVD, muffled heart sounds.
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Pulmonary vs Systemic Circulation
Right = Rest (lungs nearby) · Left = Long way (whole body)
Pulmonary circuit (short) · Systemic circuit (long)
Two circuits of circulation — why the left ventricle is thicker
Pulmonary circulation: right heart → lungs → left heart. Short circuit, low pressure — only needs to push blood to the nearby lungs. Systemic circulation: left heart → entire body → right heart. Long circuit, high pressure — needs to push blood to the feet and back. This is why the left ventricle wall is 3× thicker than the right — it must generate far more pressure. Normal systolic BP = 120 mmHg (systemic). Pulmonary artery pressure = 25 mmHg.
Pulmonary
Right heart → lungs → left heart. Low pressure (25 mmHg).
Systemic
Left heart → whole body → right heart. High pressure (120 mmHg).
LV wall
3× thicker than RV — generates high pressure for systemic circulation.
Portal circulation
Gut → liver → inferior vena cava. Liver filters absorbed nutrients first.
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🃏 Pulmonary vs Systemic Circulation
Pulmonary vs systemic circulation — which side, what pressure?
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🃏 Answer
Right = Rest (lungs nearby) · Left = Long way (whole body)
PulmonaryRight heart → lungs → left heart. Low pressure (25 mmHg).
SystemicLeft heart → whole body → right heart. High pressure (120 mmHg).
LV wall3× thicker than RV — generates high pressure for systemic circulation.
Portal circulationGut → liver → inferior vena cava. Liver filters absorbed nutrients first.
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ECG Waves
P-QRS-T — Pretty Quick Response To stimulus
P wave · QRS complex · T wave
Three ECG components — what each represents
P wave: atrial depolarization (atria contract). PR interval: conduction through AV node (delay). QRS complex: ventricular depolarization (ventricles contract) — atrial repolarization hidden here. T wave: ventricular repolarization (ventricles reset). ST segment elevation = STEMI (heart attack). Prolonged PR = heart block. Wide QRS = bundle branch block. Peaked T waves = hyperkalemia.
P wave
Atrial depolarization — SA node fires, atria contract.
PR interval
AV node delay — normal 0.12-0.20 sec. Prolonged = heart block.
QRS complex
Ventricular depolarization — normal <0.12 sec. Wide = BBB.
ST segment
Elevation = STEMI. Depression = ischemia or NSTEMI.
T wave
Ventricular repolarization. Peaked = hyperkalemia. Inverted = ischemia.
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🃏 ECG Waves
P-QRS-T
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🃏 Answer
P-QRS-T — Pretty Quick Response To stimulus
P waveAtrial depolarization — SA node fires, atria contract.
PR intervalAV node delay — normal 0.12-0.20 sec. Prolonged = heart block.
QRS complexVentricular depolarization — normal <0.12 sec. Wide = BBB.
ST segmentElevation = STEMI. Depression = ischemia or NSTEMI.
T waveVentricular repolarization. Peaked = hyperkalemia. Inverted = ischemia.
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Blood Pressure Regulation
BP = CO × PVR · CO = HR × SV
Blood Pressure = Cardiac Output × Peripheral Vascular Resistance
The fundamental equation of blood pressure — everything else follows from this
Blood pressure equals cardiac output times peripheral vascular resistance. Cardiac output = heart rate × stroke volume. Stroke volume depends on preload (filling), afterload (resistance), and contractility. Hypertension can result from increased CO (high HR or SV) or increased PVR (vasoconstriction). Baroreceptors in the carotid sinus and aortic arch detect BP changes and signal the medulla to adjust HR and vessel tone via the autonomic nervous system.
BP = CO × PVR
The master equation. Increase either → hypertension.
CO = HR × SV
Cardiac output. Normal ~5 L/min at rest.
Preload
Ventricular filling volume — Frank-Starling: more stretch = stronger contraction.
Afterload
Resistance heart pumps against — increased in hypertension.
Baroreceptors
Carotid sinus + aortic arch — detect pressure changes, reflex correction.
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🃏 Blood Pressure Regulation
Blood pressure — the two key equations?
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🃏 Answer
BP = CO × PVR · CO = HR × SV
BP = CO × PVRThe master equation. Increase either → hypertension.
CO = HR × SVCardiac output. Normal ~5 L/min at rest.
PreloadVentricular filling volume — Frank-Starling: more stretch = stronger contraction.
AfterloadResistance heart pumps against — increased in hypertension.
BaroreceptorsCarotid sinus + aortic arch — detect pressure changes, reflex correction.
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🎓 Common Exam Questions